As a stimulant, the act of taking an amphetamine can trigger a rewiring of the brain’s reward system. If a user is feeling down and unmotivated because they have not taken an amphetamine in a while, they will have the urge to continue taking it in order to feel “normal” again, as their brain and body adjusted to life with the assistance of an outside substance.
There a lot of methods to combat the withdrawal effects. Outpatient treatment programs with medical supervision is the most common, while inpatient treatment is a just as effective option. Medications are often prescribed to combat the negative withdrawal effects as well. For example, antidepressants can greatly help combat feelings of depression from the lack of amphetamines.
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